AAtlantic Commercial AdvisorsKW Commercial · South Florida

St. Lucie County Medical Offices for Sale and Lease

14 medical offices for sale and lease in St. Lucie County right now, asking $160K to $3.3M across the 14 priced listings. The newest was listed Oct 3, 2026; this page rereads the live feeds every five minutes.

Live for sale and lease
14
listings
Median asking
$555K
14 priced
Median $/SF
$235
asking, on building SF
Population
346K
ACS 2023
Median household income
$69K
ACS 2023

14 medical office properties for sale and lease in St. Lucie County right now, median asking $555K, $235 per SF. St. Lucie County has 346K people and a $69K median household income. Off-market inventory is matched to buyer criteria before it is ever listed.

Active inventory

14 medical office properties in St. Lucie County

Open in full search →
801 SW BILTMORE Street # 0
For SaleMLS
Office

801 SW BILTMORE Street # 0

Port St. Lucie, FL
$625K
Details →
1,676 SFBuilt 1984
Listed by DiFrancesco Real Estate
1405 SE Goldtree Drive
For SaleMLS
Office

1405 SE Goldtree Drive

Port St. Lucie, FL
$3.30M
Details →
11,187 SFBuilt 2000
Listed by Paradise Real Estate Intl
756 SE Port St Lucie Boulevard
For SaleMLS
Office

756 SE Port St Lucie Boulevard

Port St. Lucie, FL
$799K
Details →
3,404 SFBuilt 1994
Listed by EXP Realty LLC
1801 S 23rd Street
For SaleMLS
Office

1801 S 23rd Street

Fort Pierce, FL
$400K
Details →
1,734 SFBuilt 1988
Listed by Coldwell Banker Paradise
1912 Nebraska Avenue
For SaleMLS
Office

1912 Nebraska Avenue

Fort Pierce, FL
$625K
Details →
2,100 SFBuilt 1983
Listed by Coldwell Banker Paradise
540 NW University Boulevard # 206
For SaleMLS
Office

540 NW University Boulevard # 206

Port St. Lucie, FL
$365K
Details →
968 SFBuilt 2006
Listed by The Keyes Company
506 N 7th N
For SaleMLS
Office

506 N 7th N

Fort Pierce, FL
$230K
Details →
792 SFBuilt 1964
Listed by Lon Parsons & Associates
1505 Orange Avenue
For SaleMLS
Office

1505 Orange Avenue

Fort Pierce, FL
$2.25M
Details →
11,534 SFBuilt 1953
Listed by Equity Florida Treasure Coast LLC
602 W Midway Road
For SaleMLS
Office

602 W Midway Road

Fort Pierce, FL
$559K
Details →
1,884 SFBuilt 1960
Listed by Ultimate Realty Corp
725 SE Port St Lucie Boulevard # 204
For SaleMLS
Office

725 SE Port St Lucie Boulevard # 204

Port St. Lucie, FL
$160K
Details →
700 SFBuilt 1985
Listed by Premier Brokers International
1803 & 1805 S 25th Street
For SaleMLS
Office

1803 & 1805 S 25th Street

Fort Pierce, FL
$1.90M
Details →
9,560 SFBuilt 1980
Listed by Coastal Breeze Realty Corp
706 N 7th St
For SaleMLS
Office

706 N 7th St

Fort Pierce, FL
$550K
Details →
4,691 SFBuilt 1951
Listed by Total R E Consultants Inc
Photos coming soon
For SaleMLS
Office

781 E Prima Vista E Boulevard

Port St. Lucie, FL
$210K
Details →
Built 2100
Listed by Coldwell Banker Paradise
706 N 7th Street
For SaleMLS
Office

706 N 7th Street

Fort Pierce, FL
$550K
Details →
4,805 SFBuilt 1951
Listed by Total R E Consultants Inc
Next step

Buying or selling medical offices in St. Lucie County?

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Market overview

Medical Office in St. Lucie County

St. Lucie County is the Treasure Coast's growth engine. Port St. Lucie is one of Florida's fastest-growing cities, anchoring multifamily and retail demand. Industrial along I-95 north of PSL has emerged as a meaningful logistics corridor.

Medical office is the strongest-performing office subtype in South Florida: an aging, growing population drives structural demand, buildout cost (exam-room plumbing, imaging shielding, generators) makes tenants sticky, and health-system affiliations bring credit to the rent roll. Cleveland Clinic, Baptist Health, and HCA expansion keeps pulling private practices into competing locations.

Buyer depth is institutional: medical office REITs and funds compete with private 1031 buyers for stabilized product, and cap rates run tighter than commodity office of the same vintage. Practice owner-occupiers are a second bid for smaller condo and freestanding product.

Common questions

Frequently asked

How many medical offices are for sale and lease in St. Lucie County right now?

14 as of Oct 3, 2026, counting our own listings and the MLS feed for St. Lucie County. The count above refreshes every five minutes from the same query.

What do medical offices in St. Lucie County sell for?

Asking prices on the 14 priced listings run $160K to $3.3M, with a median of $555K and a median of $235 per square foot. Those are asking figures from today's inventory, not closed sales.

Where else are medical offices for sale and lease near St. Lucie County?

Palm Beach County medical offices for sale and lease, Broward County medical offices for sale and lease, Miami-Dade County medical offices for sale and lease. Each page carries its own live count and refreshes on the same schedule as this one.

Palm Beach County Medical Offices for Sale and Lease →

Are health care properties for sale and lease in St. Lucie County listed on this page?

Yes. Medical office, urgent care, dental, imaging and outpatient buildings are all listed as medical office here.

Do you have off-market medical office property deals in St. Lucie County?

Yes. Many of the best medical office property opportunities in St. Lucie County never reach a public listing platform. Join our off-market buyer list and we will match your criteria against pre-market inventory across St. Lucie County as it surfaces.

Does Atlantic Commercial Advisors represent buyers and sellers of Medical Office in St. Lucie County?

Yes. On the listing side we package a full Offering Memorandum with comparable sales and demographic context. On the buyer side we run a mandate that tracks your criteria against active and off-market inventory across South Florida, so nothing that fits slips past you.