AAtlantic Commercial AdvisorsKW Commercial · South Florida
Mixed-use building with ground-floor retail and residential above

St. Lucie County Mixed-Use Properties for Sale and Lease

18 mixed-use properties for sale and lease in St. Lucie County right now, asking $48K to $3.4M across the 18 priced listings. The newest was listed Oct 4, 2026; this page rereads the live feeds every five minutes.

Live for sale and lease
18
listings
Median asking
$543K
18 priced
Median $/SF
$231
asking, on building SF
Population
346K
ACS 2023
Median household income
$69K
ACS 2023

18 mixed-use properties for sale and lease in St. Lucie County right now, median asking $543K, $231 per SF. St. Lucie County has 346K people and a $69K median household income. Off-market inventory is matched to buyer criteria before it is ever listed.

Active inventory

18 mixed-use properties in St. Lucie County

Open in full search →
927 N Us Highway 1
For SaleMLS
Mixed Use

927 N Us Highway 1

Fort Pierce, FL
$3.40M
Details →
3,992 SFBuilt 1980
Listed by United Realty Group Inc
1514 SE Port St Lucie Boulevard
For SaleMLS
Mixed Use

1514 SE Port St Lucie Boulevard

Port St. Lucie, FL
$675K
Details →
2,548 SFBuilt 1978
Listed by RE/MAX Gold
3781 Oleander Avenue
For SaleMLS
Mixed Use

3781 Oleander Avenue

Fort Pierce, FL
$230K
Details →
1,533 SFBuilt 2006
Listed by Partnership Realty Inc.
3805 Okeechobee Road
For SaleMLS
Mixed Use

3805 Okeechobee Road

Fort Pierce, FL
$799K
Details →
1,080 SFBuilt 1967
Listed by Partnership Realty Inc.
1256 SW Biltmore Street
For SaleMLS
Mixed Use

1256 SW Biltmore Street

Port St. Lucie, FL
$295K
Details →
1,225 SFBuilt 2006
Listed by Reliant Realty ERA Powered
464 N 9th Street
For SaleMLS
Mixed Use

464 N 9th Street

Fort Pierce, FL
$650K
Details →
4,279 SFBuilt 1945
Listed by Echo Fine Properties
1892 SW Biltmore Street
For SaleMLS
Mixed Use

1892 SW Biltmore Street

Port St. Lucie, FL
$1.30M
Details →
2,573 SFBuilt 1976
Listed by Realty One Group Innovation
1463 SE VILLAGE GREEN Drive # A9
For SaleMLS
Mixed Use

1463 SE VILLAGE GREEN Drive # A9

Port St. Lucie, FL
$129K
Details →
484 SFBuilt 1984
Listed by Florida Realty of Miami Corp
1201 Avenue D
For SaleMLS
Mixed Use

1201 Avenue D

Fort Pierce, FL
$190K
Details →
2,686 SFBuilt 1950
Listed by 1st Prime Realty
2150 SW Imperial Street
For SaleMLS
Mixed Use

2150 SW Imperial Street

Port St. Lucie, FL
$635K
Details →
2,864 SFBuilt 2004
Listed by Lemon Drop Realty
Photos coming soon
For SaleMLS
Mixed Use

1710 Avenue E

Fort Pierce, FL
$375K
Details →
1,952 SFBuilt 1957
Listed by Treasure Coast Realty Group
117 N 5th Street
For SaleMLS
Mixed Use

117 N 5th Street

Fort Pierce, FL
$1.65M
Details →
5,644 SFBuilt 1953
Listed by Total R E Consultants Inc
Photos coming soon
For SaleMLS
Mixed Use

1712 Avenue E

Fort Pierce, FL
$450K
Details →
1,760 SFBuilt 1967
Listed by Treasure Coast Realty Group
150 SW Chamber Court
For SaleMLS
Mixed Use

150 SW Chamber Court

Port St. Lucie, FL
$48K
Details →
1,911 SFBuilt 2006
Listed by Partnership Realty Inc.
6509 St Lucie Boulevard # 2
For SaleMLS
Mixed Use

6509 St Lucie Boulevard # 2

Fort Pierce, FL
$385K
Details →
Built 2024
Listed by Savvy Avenue, LLC
1140 Avenue D
For SaleMLS
Mixed Use

1140 Avenue D

Fort Pierce, FL
$399K
Details →
4,800 SFBuilt 1980
Listed by Coldwell Banker/ Res. Real Est
2402 S US Highway 1
For SaleMLS
Mixed Use

2402 S US Highway 1

Fort Pierce, FL
$2.60M
Details →
3,250 SFBuilt 1949
Listed by BHHS EWM Realty
603 S 33rd St
For SaleMLS
Mixed Use

603 S 33rd St

Fort Pierce, FL
$780K
Details →
3,606 SFBuilt 1956
Listed by Rush Properties
Next step

Buying or selling mixed-use properties in St. Lucie County?

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Market overview

Mixed-Use in St. Lucie County

St. Lucie County is the Treasure Coast's growth engine. Port St. Lucie is one of Florida's fastest-growing cities, anchoring multifamily and retail demand. Industrial along I-95 north of PSL has emerged as a meaningful logistics corridor.

Mixed-use combines residential income with ground-floor retail or office, the highest-and-best-use solution for urban corridors. We work main-street mixed-use, transit-oriented development, and live-work product.

Buyers value the rent diversification: residential pays the debt, ground-floor retail provides the upside. Operationally complex but resilient.

Common questions

Frequently asked

How many mixed-use properties are for sale and lease in St. Lucie County right now?

18 as of Oct 4, 2026, counting our own listings and the MLS feed for St. Lucie County. The count above refreshes every five minutes from the same query.

What do mixed-use properties in St. Lucie County sell for?

Asking prices on the 18 priced listings run $48K to $3.4M, with a median of $543K and a median of $231 per square foot. Those are asking figures from today's inventory, not closed sales.

Where else are mixed-use properties for sale and lease near St. Lucie County?

Palm Beach County mixed-use properties for sale and lease, Broward County mixed-use properties for sale and lease, Miami-Dade County mixed-use properties for sale and lease. Each page carries its own live count and refreshes on the same schedule as this one.

Palm Beach County Mixed-Use Properties for Sale and Lease →

Do you have off-market mixed-use property deals in St. Lucie County?

Yes. Many of the best mixed-use property opportunities in St. Lucie County never reach a public listing platform. Join our off-market buyer list and we will match your criteria against pre-market inventory across St. Lucie County as it surfaces.

Does Atlantic Commercial Advisors represent buyers and sellers of Mixed-Use in St. Lucie County?

Yes. On the listing side we package a full Offering Memorandum with comparable sales and demographic context. On the buyer side we run a mandate that tracks your criteria against active and off-market inventory across South Florida, so nothing that fits slips past you.